Intramolecular hydrophosphination/cyclization of phosphinoalkenes and phosphinoalkynes catalyzed by organolanthanides: scope, selectivity, and mechanism

MR Douglass, CL Stern, TJ Marks

Index: Douglass; Stern; Marks Journal of the American Chemical Society, 2001 , vol. 123, # 42 p. 10221 - 10238

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Citation Number: 157

Abstract

Organolanthanide complexes of the general type Cp'2LnE (TMS) 2 (Cp'= η5-Me5C5; Ln= La, Sm, Y, Lu; E= CH, N; TMS= SiMe3) serve as effective precatalysts for the rapid intramolecular hydrophosphination/cyclization of the phosphinoalkenes and phosphinoalkynes RHP (CH2) n CH CH2 (R= Ph, H; n= 3, 4) and H2P (CH2) n C⋮ C-Ph (n= 3, 4) to afford the corresponding heterocycles CH3CH (CH2) n PR and Ph (H) CC (CH2) n ...