Palladium-catalyzed cross-coupling of vinyl iodides with organostannanes: synthesis of unsymmetrical divinyl ketones

…, ME Wright, PD Davis, SS Labadie…

Index: Goure; Wright; Davis; Labadie; Stille Journal of the American Chemical Society, 1984 , vol. 106, # 21 p. 6417 - 6422

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Citation Number: 99

Abstract

Abstract: The palladium-catalyzed cross-coupling reaction of vinyl iodides with trimethyl-or tributylvinylstannanes in the presence of carbon monoxide gives unsymmetrical divinyl ketones in good yields. The reaction conditions are neutral and mild enough (4C-50'C, 15- 50 psig carbon monoxide) that other functional groups in either coupling partner can be brought unaltered into the coupled product. The E geometry in both partners is retained in ...