Synthesis and biological evaluation of novel 2-(1H-imidazol-4-yl) cyclopropane carboxylic acids: key intermediates for H 3 histamine receptor ligands

MF Braña, C Guisado, LF Alguacil, E Garrido…

Index: Brana, Miguel F; Guisado, Cristina; Fernando Alguacil, Luis; Garrido, Elisa; Perez-Garcia, Carmen; Ruiz-Gayo, Mariano Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 24 p. 3561 - 3563

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Citation Number: 9

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A new synthetic methodology to provide cis-2-(1H-imidazol-4-yl)-cyclopropane carboxylic acids is described. These cyclopropanes are useful for the preparation of novel H 3 receptor agents. ... The synthesis of novel key intermediates for H 3 histamine ligands is reported.