Bulletin of the Chemical Society of Japan

Hexacarbonylmolybdenum-induced reaction of isoxazoles. Cycloaddition of isoxazoles with acetylenic esters and related reactions.

T Kobayashi, M Nitta

Index: Kobayashi, Tomoshige; Nitta, Makoto Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 1 p. 152 - 157

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Citation Number: 12

Abstract

In the presence of hexacarbonylmolybdenum, substituted isoxazoles undergo a cycloaddition reaction with dimethyl acetylenedicarboxylate across the C-4–C-5 bond to give 3, 4-bis (methoxycarbonyl) pyridine derivatives. In a similar cycloadition of isoxazoles with methyl propiolate, 4-(methoxycarbonyl) pyridine derivatives were also obtained. The β- carbon atom of methyl propiolate could intervene in the bonding with the C-5 position of ...