Diels-Alder reaction of heterocyclic azadienes. 2." Catalytic" Diels-Alder reaction of in situ generated enamines with 1, 2, 4-triazines: general pyridine annulation

DL Boger, JS Panek, MM Meier

Index: Boger, Dale L.; Panek, James S.; Meier, Michael M. Journal of Organic Chemistry, 1982 , vol. 47, # 5 p. 895 - 897

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Citation Number: 63

Abstract

pyridines. These studies led to the development of a simple pyridine annulation based on the regiospecific inverse electron-demand Diels-Alder reaction of enamines with 1, 2, 4- triazine (eq lh3 Despite the convenience and simplicity of this pyridine annulation, two immediate limitations surfaced which have proven to restrict the applicability of the reaction. First there is the requirement for a preformed pyrrolidine enamine, a venture approached ...