An imidazole-functionalized phosphatidylcholine derivative: nucleophilic vesicles with adjustable reactivity

…, P Scrimin, S Bhattacharya, S Swarup

Index: Moss, Robert A.; Scrimin, Paolo; Bhattacharya, Santanu; Swarup, Shanti Journal of the American Chemical Society, 1987 , vol. 109, # 20 p. 6209 - 6210

Full Text: HTML

Citation Number: 15

Abstract

In connection with our quest for locus specific vesicular chemistry, 2 we sought a nucleophile-functionalized, vesicle-forming surfactant3 with a “natural” acylglycerol backbone. We have already described the (dihexadecylmethylethy1ammonio)- carboxyimidazole surfactant 1, 4 We are pleased to report here the synthesis of an imidazole- derivatized phosphatidylcholine (2) and the remarkable kinetic behavior of vesicles ...