Tetrahedron letters

Conjugate addition of silyl groups to β-unsubstituted enones, & Si-to-OH conversion: a synthesis of (±)-lavandulol

I Fleming, D Lee

Index: Fleming, Ian; Lee, Duckhee Tetrahedron Letters, 1996 , vol. 37, # 38 p. 6929 - 6930

Full Text: HTML

Citation Number: 15

Abstract

TMS chloride raises the yield in the conjugate addition of silylcuprates and zincates to β- unsubstituted enones, and Si-to-OH conversion is possible using the 2-methylbut-2-enyl (diphenyl) silyl group in the presence of highly nucleophilic alkenes. Both reactions are used