Design of receptors for urea derivatives based on the pyrido [3, 2-g] indole subunit

…, P Madhukar, R Cunningham, T Hopfner…

Index: Hegde, Vidyadhar; Hung, Chi-Ying; Madhukar, Puttannachetty; Cunningham, Raymond; Hoepfner, Thomas; Thummel, Randolph P. Journal of the American Chemical Society, 1993 , vol. 115, # 3 p. 872 - 878

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Citation Number: 75

Abstract

Abstract: The Fischer cyclization of appropriate 8-quinolinylhydrazones was employed to prepare a series of cavity-shaped hosts consisting of a central pyridine ring appended in either the 2, 6-or 3, 5-positions by two pyrido [3, 2-g] indole subunits. The pyridine and pyridoindole moieties were further connected by dimethylene or trimethylene bridges which control the shape of the cavity. Hosts having a dimethylene bridge evidenced a strong ...