The Journal of Organic Chemistry

Reactions of Dicarboximidophosphonothioate Esters with Nucleophilic Reagents

DW Osborne

Index: Osborne,D.W. Journal of Organic Chemistry, 1966 , vol. 31, p. 197 - 200

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Citation Number: 0

Abstract

0, O-Diethyl phthalimidophosphonothioate reacts with aniline, isopropylamine, p- nitrophenylhydrazine, SO-dium methoxide, potassium hydroxide, and sodium borohydride by displacement on the carbonyl carbon to produce N-(diethoxyphosphinothioy1) phthalamic acid derivatives, with sodium p-chlorophenate by displacement on phosphorus, and with thiourea by displacement on saturated carbon. The alkaline hydrolysis is first ...