Enzymatic Baeyer–Villiger Oxidation of Benzo??Fused Ketones: Formation of Regiocomplementary Lactones

A Rioz??Martínez, G de Gonzalo…

Index: Rioz-Martinez, Ana; De Gonzalo; Torres Pazmino, Daniel E.; Fraaije, Marco W.; Gotor, Vicente European Journal of Organic Chemistry, 2009 , # 15 p. 2526 - 2532

Full Text: HTML

Citation Number: 26

Abstract

Abstract Baeyer–Villiger monooxygenases (BVMOs) are enzymes that are known to catalyse the Baeyer–Villiger oxidation of ketones in aqueous media using O 2 as oxidant. Herein, we describe the oxidation of a set of diverse benzo-fused ketones by three different BVMOs in both aqueous and non-conventional reaction media. Most of the tested ketones, for example, 1-tetralone and 1-and 2-indanone, were converted by one of the employed ...