New method for selective monofluorination of aromatics using silver difluoride

A Zweig, RG Fischer, JE Lancaster

Index: Zweig, Arnold; Fischer, Robert G.; Lancaster, John E. Journal of Organic Chemistry, 1980 , vol. 45, # 18 p. 3597 - 3603

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Citation Number: 34

Abstract

Fluorobenzene is obtained in 61% yield from reaction of a solution of benzene in n-hexane with solid argentic fluoride (AgF2.). The AgFz acta as both a strong oxidant and the fluoride source. Cobaltic fluoride provides only low (43%) yields of fluorobenzene under similar conditions. The predominant reaction of benzene solutions with AgFz appears to proceed by a process involving initial electrophilic oxidative cis addition of two fluorine atoms from the ...