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Rhodium-catalyzed synthesis of isothiocyanate from isonitrile and sulfur

M Arisawa, M Ashikawa, A Suwa, M Yamaguchi

Index: Arisawa, Mieko; Ashikawa, Masanori; Suwa, Atsushi; Yamaguchi, Masahiko Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1727 - 1729

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Citation Number: 19

Abstract

Rhodium complexes RhH (PPh3) 4 and Rh (acac)(CH2CH2) 2 catalyze sulfuration of isonitrile with sulfur giving isothiocyanates in high yields. The metal-catalyzed reaction is rapid in refluxing acetone, and completes within 3h in most cases. The reaction exhibits induction period, which disappeared by preheating sulfur in refluxing acetone for 1.5 h. Use of several organic polysulfides in this transformation was examined in order to compare ...