A convenient synthesis of novel 3-(heterocyclylsulfonyl) propanoic acids and their amide derivatives

…, EE Shalygina, DV Kravchenko, AV Ivachtchenko

Index: Dorogov, Mikhail V.; Filimonov, Sergey I.; Kobylinsky, Dmitry B.; Ivanovsky, Sergey A.; Korikov, Pavel V.; Soloviev, Mikhail Y.; Khahina, Maria Y.; Shalygina, Elena E.; Kravchenko, Dmitry V.; Ivachtchenko, Alexandre V. Synthesis, 2004 , # 18 p. 2999 - 3004

Full Text: HTML

Citation Number: 3

Abstract

Abstract A large number of novel 3-(heterocyclylsulfonyl) propanoic acids and their amide derivatives were prepared in good yields and excellent purity starting from the corresponding heterocyclic compounds. At first, chlorosulfonates were generated by reaction of initial heterocycles with various sulfonating and chlorinating agents followed by their conversion into sodium sulfinates. Treatment of sulfinates with acrylic acid smoothly ...