The Journal of Organic Chemistry

A New Method for the Preparation of 1-Ethynyl Ethers

JA Cabezas, AC Oehlschlager

Index: Cabezas, Jorge A.; Oehlschlager, Allan C. Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7523 - 7525

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Citation Number: 6

Abstract

During our study2 of the stannylcupration of acetylenic ethers we required [2J3C]-l for mechanistic studies. Existing methods3 for the synthesis of acetylenic ethers involve dehydrohalogenation of 2-halo, 4 1, a-dihalo vinyl ether^,^ or haloacetals6 using KOH, NaNH2, or n-BuLi. These procedures are incompatible with labile functional groups and, if applied to the preparation of 13C-labeled compounds, would require regiospecific ...