Silver-catalyzed late-stage fluorination

P Tang, T Furuya, T Ritter

Index: Tang, Pingping; Furuya, Takeru; Ritter, Tobias Journal of the American Chemical Society, 2010 , vol. 132, # 34 p. 12150 - 12154

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Citation Number: 208

Abstract

Carbon− fluorine bond formation by transition metal catalysis is difficult, and only a few methods for the synthesis of aryl fluorides have been developed. All reported transition- metal-catalyzed fluorination reactions for the synthesis of functionalized arenes are based on palladium. Here we present silver catalysis for carbon− fluorine bond formation. Our report is the first example of the use of the transition metal silver to form carbon− ...