A Chiral Lewis Acid Strategy for Enantioselective Allylic C H Oxidation

DJ Covell, MC White

Index: Covell, Dustin J.; White, M. Christina Angewandte Chemie - International Edition, 2008 , vol. 47, # 34 p. 6448 - 6451

Full Text: HTML

Citation Number: 151

Abstract

CÀH oxidation reactions have the potential to significantly streamline synthetic processes. However, to be useful for the synthesis of complex molecules, these reactions must proceed with high levels of chemo-, regio-, and stereoselectivity. Chiral bisoxazoline/copper- catalyzed systems have shown promising levels of asymmetric induction in the enantioselective allylic CÀH esterification of symmetrical, cyclic olefins. Application of ...