Tetrahedron

Solid-state organic reactions proceeding by pulverization: Oxidation and halogenation with iodosobenzene and inorganic solid-supports

H Sohmiya, T Kimura, M Fujita, T Ando

Index: Sohmiya, Hajime; Kimura, Takahide; Fujita, Mitsue; Ando, Takashi Tetrahedron, 1998 , vol. 54, # 45 p. 13737 - 13750

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Citation Number: 27

Abstract

Pulverization-activation method was employed to accelerate solid-state organic reactions. Crushing and grinding of solid mixtures of hydrogen halide-treated silica gels, iodosobenzene and organic substrates in the absence of a solvent brought about smooth and rapid reactions to give halogenated and/or oxidized products in good yields. Various sulfides were smoothly converted to sulfonyl chlorides in one step in excellent yields. The ...

~90%

~49%

~89%

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~90%

~80%

~73%

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