Chemistry letters

Palladium-Catalyzed Benzylic CH Borylation of Alkylbenzenes with Bis (pinacolato) diboron or Pinacolborane.

T Ishiyama, K Ishida, J Takagi, N Miyaura

Index: Ishiyama, Tatsuo; Ishida, Kousaku; Takagi, Jun; Miyaura, Norio Chemistry Letters, 2001 , # 11 p. 1082 - 1083

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Citation Number: 70

Abstract

Borylation at the benzylic C–H bond of alkylbenzenes with bis (pinacolato) diboron [(Me 4 C 2 O 2) B–B (O 2 C 2 Me 4)] or pinacolborane [(Me 4 C 2 O 2) B–H] was carried out at 100° C in the presence of a catalytic amount of 10% Pd/C. The reaction selectively afforded pinacol benzylboronates in good yields directly from various alkylbenzenes.