Tetrahedron

Synthesis of short and long chain cardiolipins

…, MU Ahmad, P Koslosky, K Kasireddy, UM Krishna…

Index: Ali, Shoukath M.; Ahmad, Moghis U.; Koslosky, Peter; Kasireddy, Krishnudu; Murali Krishna; Ahmad, Imran Tetrahedron, 2006 , vol. 62, # 29 p. 6990 - 6997

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Citation Number: 3

Abstract

A phosphoramidite approach using 2-cyanoethyl N, N-diisopropylchlorophosphoramidite was utilized for the first time to synthesize short chain cardiolipins. The approach was extended to synthesize long chain and their ether analogue. Optically active 1, 2-di-O-acyl- sn-glycerol or 1, 2-di-O-myristyl-sn-glycerol was coupled with phosphoramidite reagent and 2-benzyloxy-1, 3-propanediol in presence of 1H-tetrazole, followed by in situ oxidation, to ...