Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno [3, 4-b] pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens

S Purushothaman, R Prasanna, P Niranjana…

Index: Purushothaman; Prasanna; Niranjana; Raghunathan; Nagaraj; Rengasamy Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 24 p. 7288 - 7291

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Citation Number: 19

Abstract

Synthesis of a series of novel hexahydrochromenopyrrole analogues has been accomplished through an intramolecular 1, 3-dipolar cycloaddition (1, 3-DC reaction) of azomethine ylides, generated by the aldehyde induced decarboxylation of secondary ...