" Key:(a) m-CPBA/CH2C1,;(b) NaOH (92%);(ci DHP/H+(88%);(d) n-BuLi;(e) DMF;(f) H30+(79%). 22 in 64% overall yield is outlined in Scheme VI. Here, 2, 5- dimethoxybenzaldehyde (29) was converted to the phenol 30 in 92% yield. The THP derivative 31 was prepared in 88% yield, and subsequent formylation and deprotection gave 22 in 79% yield. Still another route to 22 was achieved in 41% yield starting with the ...
