The Journal of Organic Chemistry

Amino Acid Analogs. I. Analogs of the Glutamic Acid, Proline Interconversion. Part I. ι-Methyl-and ι-Phenylketoglutamic Acids and 5-Methyl-and 5-Phenylprolines

H GERSHON, A SCALA

Index: Gershon,H.; Scala,A. Journal of Organic Chemistry, 1961 , vol. 26, p. 2347 - 2350

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Citation Number: 14

Abstract

VOL. 26 2348 GERSHON AND SCALA acid; r proline. Since this sequence seems to be a major metabolic pathway for both glutamic acid and proline, it was of interest to prepare analogs of these compounds and their respective intermediates in order to determine whether, by this means, metabolic inhibition could be achieved. I t was reported by Ginsburg, Lovett, and Dunn3 that the strain of tuberculosis bacteria, which infects humans, ...