Iridium-Catalyzed Alkylation of Methylquinolines with Alcohols

Y Obora, S Ogawa, N Yamamoto

Index: Obora, Yasushi; Nakamura, Kazuhiro; Hatanaka, Shintaro Chemical Communications, 2012 , vol. 48, # 53 p. 6720 - 6722

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Citation Number: 30

Abstract

Iridium-catalyzed alkylation of methylquinolines at the methyl substituent was achieved using alcohols as alkylating agents. The reaction proceeded through a transfer hydrogenation pathway from the alcohol to the Ir complex, affording an aldehyde and Ir–H