Tetrahedron Letters

Synthesis of azo compounds by nanosized iron-promoted reductive coupling of aromatic nitro compounds

Y Moglie, C Vitale, G Radivoy

Index: Moglie, Yanina; Vitale, Cristian; Radivoy, Gabriel Tetrahedron Letters, 2008 , vol. 49, # 11 p. 1828 - 1831

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Citation Number: 49

Abstract

Treatment of a variety of aromatic nitro compounds with the active-iron based reducing system composed of FeCl2· 4H2O, an excess of lithium powder and a catalytic amount of 4, 4′-di-tert-butylbiphenyl (DTBB, 5mol%) in THF at room temperature, led to the formation of the corresponding symmetrically substituted azo compounds in good yield, resulting from a reductive coupling process. Some other functionalities including carbonyl, halogen, amino ...