… of 2??methoxy??4, 9??dimethyl??1??nitroacridine with selenous acid and selenium (IV) oxide. Synthesis of 1H??selenopheno [2, 3, 4??k, l] acridine??1??one: A new seleno?? …

…, EN Sigida, NN Balaneva, PS Dmitrenok…

Index: Radchenko, Oleg S.; Sigida, Elena N.; Balaneva, Nadezhda N.; Dmitrenok, Pavel S.; Novikov, Vyacheslav L. Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 1 p. 209 - 214

Full Text: HTML

Citation Number: 2

Abstract

Abstract Unusual course of the reaction was revealed on the oxidation of functionally substituted acridine containing the activated methyl groups by well-known oxidants, such as selenous acid and selenium (IV) oxide. Treatment of 2-methoxy-4, 9-dimethyl-1-nitroacridine (5) with an excess of H 2 SeO 3 in boiling ethanol gave a mixture of the normal reaction products, 2-methoxy-4-methyl-1-nitro-9-formylacridine (11)(isolated yield 29%) and 2- ...