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Deracemisation of β-hydroxy esters using immobilised whole cells of Candida parapsilosis ATCC 7330: substrate specificity and mechanistic investigation

SK Padhi, D Titu, NG Pandian, A Chadha

Index: Padhi, Santosh Kumar; Chadha, Anju Synlett, 2003 , # 5 p. 639 - 642

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Citation Number: 43

Abstract

Deracemisation of aryl substituted β-hydroxy esters by immobilised whole cells of Candida parapsilosis ATCC 7330 gave> 99% ee and up to 75% yield of their corresponding (S)- enantiomers. Mechanistic investigation of the deracemisation reaction carried out using a