Palladium??Catalyzed Formation of Highly Substituted Naphthalenes from Arene and Alkyne Hydrocarbons

YT Wu, KH Huang, CC Shin…

Index: Wu, Yao-Ting; Huang, Ke-Hsin; Shin, Chien-Chueh; Wu, Tsun-Cheng Chemistry - A European Journal, 2008 , vol. 14, # 22 p. 6697 - 6703

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Citation Number: 61

Abstract

Abstract Several highly substituted naphthalenes 3 have been synthesized in a one-pot reaction by treatment of arenes 1 with alkynes 2 in the presence of palladium acetate and silver acetate. In this Pd-catalyzed protocol, an arene provides a benzo source for the construction of a naphthalene core through twofold aryl C [BOND] H bond activation. Reaction of triphenylphosphine with diphenylethyne (2 a) under the catalysis of Pd IV ...