Total syntheses of indicine N-oxide, intermedine N-oxide, and their enantiomers using carbohydrate as a chiral educt

Y Nishimura, S Kondo, T Takeuchi…

Index: Nishimura; Kondo; Takeuchi; Umezawa Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4107 - 4113

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Citation Number: 12

Abstract

The first completely enantioselective syntheses of indicine N-oxide, intermedine N-oxide, and their enantiomers have been achieved stereospecifically. A synthetic analogue modeled on indicine N-oxide showed the superior activity to indicine N-oxide itself against cancer cell in vitro test.