Tandem supramolecular synthesis of substituted 2-aryl-2, 3-dihydroquinazolin-4 (1H)-ones in the presence of β-cyclodextrin in water

…, K Karnakar, G Satish, KHV Reddy, YVD Nageswar

Index: Ramesh; Karnakar; Satish; Harsha Vardhan Reddy; Nageswar Tetrahedron Letters, 2012 , vol. 53, # 45 p. 6095 - 6099

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Citation Number: 22

Abstract

Substituted 2-aryl-2, 3-dihydroquinazolin-4 (1H)-ones were prepared for the first time in water under neutral conditions by the reaction of aniline, isatoic anhydride, and aldehyde mediated by β-cyclodextrin in good yields. β-Cyclodextrin can be recovered and reused with a little loss of catalytic activity.