Total synthesis of ochnaflavone

MM Ndoile, FR van Heerden

Index: Ndoile, Monica M.; Van Heerden, Fanie R. Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1346 - 1351

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Citation Number: 2

Abstract

Abstract The first total syntheses of ochnaflavone, an asymmetric biflavone consisting of apigenin and luteolin moieties, and the permethyl ether of 2, 3, 2'', 3''- tetrahydroochnaflavone have been achieved. The key steps in the synthesis of ochnaflavone were the formation of a diaryl ether and ring cyclization of an ether-linked dimeric chalcone to assemble the two flavone nuclei. Optimal experimental conditions for ...