SmI2-mediated reduction of γ, γ-difluoro-α, β-enoates with application to the synthesis of functionalized (Z)-fluoroalkene-type dipeptide isosteres

A Otaka, J Watanabe, A Yukimasa…

Index: Ibuka, Toshiro; Aoyagi, Takeshi; Yamamoto, Yoshinori Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 6 p. 2417 - 2427

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Citation Number: 82

Abstract

... Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan, and Fujisawa Pharmaceutical Co., Ltd ... one-electron reducing agent capable of meeting the diverse demands of synthetic organic chemistry. ... the γ,γ-difluoro-α,β-enoates 10 proved to improve the chemical yields (67 ...