Certain 2-Furano-4 (3H)-Quinazolinone Analogs: Synthesis, Characterization and Pharmacological Evaluation

V Bhardwaj, P Sharma, MN Noolvi…

Index: Bhardwaj, Varun; Sharma, Poonam; Noolvi, Malleshappa N.; Patel, Harun M.; Bansal, Sumit; Lohan, Sandeep; Badola, Gaurav Letters in Drug Design and Discovery, 2013 , vol. 10, # 4 p. 360 - 368

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Abstract

A series of new of 2-furano-4 (3H)-quinazolinone derivatives 5 (at) were synthesized. The compounds were characterized by their IR, 1H NMR, 13C NMR, and Mass spectral data. The antimicrobial activity of newly anthranilic acid-based compounds against various bacteria; S. aureus, Salmonella enterica, Vibrio cholerae, Bacillus subtilis, Proteus mirabili, Escherichia coli V517, Mycobacterium smegmatics, Pseudomonas aeruginosa and fungi; ...