Tetrahedron letters

A concise route to phytosphingosine from lyxose

CC Lin, GT Fan, JM Fang

Index: Lin, Chun-Cheng; Fan, Gang-Ting; Fang, Jim-Min Tetrahedron Letters, 2003 , vol. 44, # 28 p. 5281 - 5283

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Citation Number: 34

Abstract

Phytosphingosine was synthesized from the commercially available d-2, 3-O-isopropylidene- d-lyxofuranose in 28% overall yield by a six-step procedure. This procedure is expedient and flexible for introduction of other lipid moieties on the phytosphingosine structure to make