Acylation studies in the thiophene and furan series. V. Thiophene carboxylic acids and semicarbazones derived from acetylthiophenes

HD Hartough, LG Conley

Index: Hartough; Conley Journal of the American Chemical Society, 1947 , vol. 69, p. 3096

Full Text: HTML

Citation Number: 47

Abstract

The semicarbazones form easily in nearly quantitative yields but are somewhat unsuitable for identification purposes in that nearly all melt above 200'and most of them are extremely insoluble in most common solvents and are difficult to recrystallize. Despite recrystallization difficulties samples of high purity are obtained without recrystallization by digesting first with water and then with alcohol to remove impurities.