Über den sterischen Verlauf der Umsetzung von Enaminen aus offenkettigen Aldehyden und Ketonen mit Nitroolefinen zu 2, 3??disubstituierten 4??Nitroketonen

D Seebach, AK Beck, J Goliński, JN Hay…

Index: Seebach, Dieter; Beck, Albert K.; Golinski, Jerzy; Hay, John N.; Laube, Thomas Helvetica Chimica Acta, 1985 , vol. 68, p. 162 - 172

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Citation Number: 67

Abstract

The relative configuration of the nitro-ketone 12 obtained by the title reaction has been proved by a Bueyer-Villiger degradation and subsequent reduction to the amino-alcohol (f)- (u)-20, the relative configuration of which is identical with a sample prepared from 2-methyl- 3-hydroxyhutyrate of known configuration (Scheme I). The stereochemical course of the title reaction is thus as predicted by our topological rule. It is assumed that the other nitro- ...