The chemical synthesis of bioactive glycosylphosphatidylinositols from Trypanosoma cruzi containing an unsaturated fatty acid in the lipid

DV Yashunsky, VS Borodkin…

Index: Yashunsky, Dmitry V.; Borodkin, Vladimir S.; Ferguson, Michael A. J.; Nikolaev, Andrei V. Angewandte Chemie - International Edition, 2006 , vol. 45, # 3 p. 468 - 474

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Citation Number: 51

Abstract

Glycosylphosphatidylinositols (GPIs) are a class of natural glycosylphospholipids that anchor proteins and glycoproteins (through their Cterminus) as well as phosphoglycans (through the reducing end of the chain) to the membrane of eukaryotic cells. Since the first full assignment of a GPI structure in 1988,[1] a number of GPI anchors have been characterized.[2] The function of the compounds, in addition to the clear one of linking the ...

Regiospecific opening of glycidyl derivatives mediated by bo...

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Lipase-catalysed kinetic resolution of 1-O-alkylglycerols by...

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Synthesis of 2-O-Acetyl-3-O-hexadecyl-sn-1-glycerylphosphory...

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Autotaxin structure–activity relationships revealed through ...

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