Tetrazoles: LIV. Alkylation of 5-aryltetrazoles under microwave activation

YA Efimova, TV Artamonova, GI Koldobskii

Index: Efimova; Artamonova; Koldobskii Russian Journal of Organic Chemistry, 2009 , vol. 45, # 5 p. 725 - 727

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Citation Number: 3

Abstract

Abstract The application of microwave activation (MWA) to alkylation of 5-aryltetrazoles with dimethyl sulfate in organic solvents did not considerably affect the selectivity of the process compared to nonactivated procedure. A significant enhancement of the selectivity to the formation of N 2-methyl-isomer occurred only in the alkylation in the dimethyl sulfate solution.