Aryloxyalkylaminoguanidines. Their Synthesis and Biological Properties

J Augstein, SM Green, AM Monro…

Index: Augstein,J. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 391 - 400

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Citation Number: 22

Abstract

Proton magnetic resonance has been iised to show that the productr of guanylation of aryloxyethylhydraziiieq are (aryloxyethy1amino) giianidines. Several such aminoguanidines containing chlorine and methyl substitiieiits in the aromatic ring have been showli 1 o possebs adrenergic nc1iron blocking properties ant1 to inhihit dopamine 6'-oxidase in vitTo.