Abstract A series of aliphatic and benzylic bifunctional boronate esters have been prepared as potential ligands for affinity chromatography. α-Acetamido, picolino, thioureido and acetamidino boronates have the hetero atom coordinated with the boron, creating a tetrahedral structure. The 1 H, 13 C and 11 B NMR for these compounds confirm the structure, as well as the hetero atom—boron coordination, and show that the bonding of ...