In search of better bioactive compounds, a series of novel 2, 6-bis [(3-aryl)-s-triazolo [3, 4-b]- [1, 3, 4] thiadiazole-6-yl] pyridines 2 were synthesized in high yields by the cyclization of 3- aryl-4-amino-5-mercapto-1, 2, 4-triazoles 1 with 2, 6-pyridine dicarboxylic acid. 2 exhibited good fungicidal activities against Cerospora beticola sacc.
[Mohan, Jag; Anjaneyulu, G. S. R.; Kiran Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 128 - 131]