Synthetic communications

A New Synthesis Of 1, 3, 4-Oxadiazoles. Cyclization Of N. N'-Diacylhydrazeves Catalyzed By Palladium (0)

S Lutun, B Hasiak, D Couturier

Index: Lutun, Stephane; Hasiak, Bruno; Couturier, Daniel Synthetic Communications, 1999 , vol. 29, # 1 p. 111 - 116

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Citation Number: 20

Abstract

Abstract Several 1, 3, 4-oxadiazoles were synthetized by cyclization of N, N'- diacylhydrazines catalyzed by palladium (O). Water formed during the reaction is responsible for the hydrolysis of the products. To avoid it, we introduced benzoic anhydride into the medium and obtained an increased yield of oxadiazoles.