Tetrahedron letters

Neopentyl ester protecting groups for arylsulfonic acids

JC Roberts, H Gao, A Gopalsamy, A Kongsjahju…

Index: Roberts, John C.; Huai, Gao; Gopalsamy, Ariamala; Kongsjahju, Azis; Patch, Raymond J. Tetrahedron Letters, 1997 , vol. 38, # 3 p. 355 - 358

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Citation Number: 38

Abstract

We report that neopentylsulfonate esters are stable to a variety of standard organic reaction conditions and are easily cleaved to sulfonic acids. We also discuss the use of N-Boc-4- amino-2, 2-dimethylbutyl-1-sulfonate esters which may be cleaved under conditions that are suitable for solid phase synthesis.