A catalytic system has been developed that used an iron/ligand combination for the Sonogashira cross coupling of terminal alkynes with aryl iodides, which affords products in good to excellent yields. ... Keywords: iron-catalysis, terminal alkynes, aryl iodides, sonogashira reaction ... * Correspondent. E-mail: mcl_wzu@yahoo.com.cn ... The Sonogashira reaction of aryl halides with terminal acetylenes, which provides a powerful tool for the formation of alkynes, has ...