Tetrahedron letters

Synthesis of the spiroketal segment (C19 C34) of the rutamycins, antifungal metabolites of Streptomyces species

JD White, Y Ohba, WJ Porter, S Wang

Index: White, James D.; Ohba, Yoshihiro; Porter, Warren J.; Wang, Shan Tetrahedron Letters, 1997 , vol. 38, # 18 p. 3167 - 3170

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Citation Number: 10

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A convergent synthesis of the spiroketal subunit of rutamycins A and B has been devised via Julia coupling of sulfone 14 with aldehyde 23; the pentahydroxy ketone 3 derived from 25 underwent spontaneous cyclization to spiroketal 4. ... Julia coupling of sulfone 14 with aldehyde 23 ...