Bulletin of the Chemical Society of Japan

Anodic cyanation of 1-methylimidazoles.

K Yoshida, H Kitabayashi

Index: Yoshida, Kunihisa; Kitabayashi, Hirohito Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 10 p. 3693 - 3696

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Citation Number: 9

Abstract

The electrooxidation of several 1-methylimidazoles was performed in MeOH that contains NaCN at a platinum anode in a divided cell. Replacement of an aromatic hydrogen by a cyano group occurred. With 1, 2, 4, 5-tetramethylimidazole, the 2, 5-addition of cyano groups to the imidazole ring was achieved, and besides side-chain substitution occurred concurrently.

~17%

Detail

~78%

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