The Journal of Organic Chemistry

Synthesis of (2, 2, 2-trifluoroethyl) benzene derivatives

A Ando, T Miki, I Kumadaki

Index: Ando, Akira; Miki, Takuichi; Kumadaki, Itsumaro Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3637 - 3639

Full Text: HTML

Citation Number: 23

Abstract

Organic fluorine compounds containing a trifluoromethyl group have lately attracted considerable attention because of their biological activities. 2 In previous papers, we reported the triflu~ romethylation~ of aromatic halides with trifluoromethyl copper and the trifluor~ propylation~ of aromatic compounds by the Friedel-Crafts reaction of trifluoropropene in the presence of HBFl as a catalyst. In (1 j A part of this work was ...