Studies on Metabolites of Macrophoma commelinae. IV.: Substrate Specificity in the Biotransformation of 2-Pyrones to Substituted Benzoic Acids

I Sakurai, H Miyajima, K Akiyama…

Index: Sakurai, Ikuo; Miyajima, Hisae; Akiyama, Katsuyoshi; Shimizu, Sakae; Yamamoto, Yuzuru Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, p. 2003 - 2011

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Citation Number: 26

Abstract

抄録: Substrate specificity in the novel biotransformation from 2-pyrone derivatives to substituted benzoic acids by Macrophoma commelinae (IFO 9570) was investigated by means of feeding experiments with various compounds. Among them, 2-pyrone derivatives substituted by an electron-donating group at C-4, by an electron-withdrawing group at C-5 and by an alkyl group at C-6 were converted to the corresponding benzoic acid ...