e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Compounds with antiulcer and antisecretory activity. III: N-substituted imidazolones condensed with nitrogen-containing heteroaromatic rings

M Bianchi, A Butti, S Rossi, F Barzaghi…

Index: Bianchi; Butti; Rossi; et al. European Journal of Medicinal Chemistry, 1983 , vol. 18, # 6 p. 501 - 506

Full Text: HTML

Citation Number: 17

Abstract

... III: N-substituted imidazolones condensed with nitrogen-containing heteroaromatic rings. Auteur(s) / Author(s). BIANCHI M. ; BUTTI A. ; ROSSI S. ; BARZAGHI F. ; MARCARIA V. ; Affiliation(s) du ou des auteurs / Author(s) Affiliation(s). Univ. Milano, ist. ...

2-Methylamino-3-nitro-6-chloropyridine Structure

2-Methylamino-3...

~%

6-CHLORO-N2-METHYLPYRIDINE-2,3-DIAMINE Structure

6-CHLORO-N2-MET...

2,6-Dichloro-3-nitropyridine Structure

2,6-Dichloro-3-...

~%

6-CHLORO-N2-METHYLPYRIDINE-2,3-DIAMINE Structure

6-CHLORO-N2-MET...

6-CHLORO-N2-METHYLPYRIDINE-2,3-DIAMINE Structure

6-CHLORO-N2-MET...

N,N-Carbonyldiimidazole Structure

N,N-Carbonyldii...

~53%

5-chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-chloro-3-meth...

2,6-Dichloro-3-nitropyridine Structure

2,6-Dichloro-3-...

~%

5-chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-chloro-3-meth...

2-Methylamino-3-nitro-6-chloropyridine Structure

2-Methylamino-3...

~%

5-chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-chloro-3-meth...

5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-Chloro-1H-imi...

methyl iodide Structure

~28%

5-chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-chloro-3-meth...

5-chloro-1,3-dimethylimidazo[4,5-b]pyridin-2-one Structure

5-chloro-1,3-di...

5-Chloro-2-pyridinamine Structure

5-Chloro-2-pyri...

Ethyl chloroformate Structure

Ethyl chloroformate

~82%

ethyl (2-chloro-5-pyridyl)carbamate Structure

ethyl (2-chloro...

ethyl (2-chloro-5-pyridyl)carbamate Structure

ethyl (2-chloro...

~62%

ethyl N-(6-chloro-2-nitropyridin-3-yl)carbamate Structure

ethyl N-(6-chlo...

5-Chloro-2-pyridinamine Structure

5-Chloro-2-pyri...

~%

ethyl N-(6-chloro-2-nitropyridin-3-yl)carbamate Structure

ethyl N-(6-chlo...

5-Chloro-2-pyridinamine Structure

5-Chloro-2-pyri...

~%

ethyl N-[(6-chloro-2-nitropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(6-chl...

ethyl (2-chloro-5-pyridyl)carbamate Structure

ethyl (2-chloro...

~%

ethyl N-[(6-chloro-2-nitropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(6-chl...

ethyl N-(6-chloro-2-nitropyridin-3-yl)carbamate Structure

ethyl N-(6-chlo...

Dimethyl sulfate Structure

Dimethyl sulfate

~%

ethyl N-[(6-chloro-2-nitropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(6-chl...

2-chloro-9-phenyl-7H-purin-8-one Structure

2-chloro-9-phen...

Dimethyl sulfate Structure

Dimethyl sulfate

~90%

2-chloro-7-methyl-9-phenylpurin-8-one Structure

2-chloro-7-meth...

2-chloro-5-nitro-N-phenylpyrimidin-4-amine Structure

2-chloro-5-nitr...

~%

2-chloro-7-methyl-9-phenylpurin-8-one Structure

2-chloro-7-meth...

2-chloro-4-phenylamino-5-aminopyrimidine Structure

2-chloro-4-phen...

~%

2-chloro-7-methyl-9-phenylpurin-8-one Structure

2-chloro-7-meth...

6-chloro-3-nitro-N-phenylpyridin-2-amine Structure

6-chloro-3-nitr...

~%

ethyl N-(2-anilino-6-chloropyridin-3-yl)carbamate Structure

ethyl N-(2-anil...

Ethyl chloroformate Structure

Ethyl chloroformate

2-phenylamino-3-amino-6-chloropyridine Structure

2-phenylamino-3...

~92%

ethyl N-(2-anilino-6-chloropyridin-3-yl)carbamate Structure

ethyl N-(2-anil...

ethyl N-[(6-chloro-2-nitropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(6-chl...

~70%

ethyl N-[(2-amino-6-chloropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(2-ami...

5-Chloro-2-pyridinamine Structure

5-Chloro-2-pyri...

~%

ethyl N-[(2-amino-6-chloropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(2-ami...

ethyl (2-chloro-5-pyridyl)carbamate Structure

ethyl (2-chloro...

~%

ethyl N-[(2-amino-6-chloropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(2-ami...

ethyl N-(6-chloro-2-nitropyridin-3-yl)carbamate Structure

ethyl N-(6-chlo...

~%

ethyl N-[(2-amino-6-chloropyridin-3-yl)methyl]carbamate Structure

ethyl N-[(2-ami...

2,6-Dichloro-3-nitropyridine Structure

2,6-Dichloro-3-...

methylamine Structure

~67%

N*2*,N*6*-Dimethyl-3-nitro-pyridine-2,6-diamine Structure

N*2*,N*6*-Dimet...

2-Methylamino-3-nitro-6-chloropyridine Structure

2-Methylamino-3...

2,6-Dichloro-3-nitropyridine Structure

2,6-Dichloro-3-...

methylamine Structure

~0%

N*2*,N*6*-Dimethyl-3-nitro-pyridine-2,6-diamine Structure

N*2*,N*6*-Dimet...

2-Methylamino-3-nitro-6-chloropyridine Structure

2-Methylamino-3...

5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-Chloro-1H-imi...

methyl iodide Structure

~28%

5-chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one Structure

5-chloro-3-meth...

5-chloro-1,3-dimethylimidazo[4,5-b]pyridin-2-one Structure

5-chloro-1,3-di...

2-chloro-5-nitro-N-phenylpyrimidin-4-amine Structure

2-chloro-5-nitr...

~%

2-chloro-9-phenyl-7H-purin-8-one Structure

2-chloro-9-phen...

2-chloro-4-phenylamino-5-aminopyrimidine Structure

2-chloro-4-phen...

N,N-Carbonyldiimidazole Structure

N,N-Carbonyldii...

~47%

2-chloro-9-phenyl-7H-purin-8-one Structure

2-chloro-9-phen...