The catalytic activity of ortho-palladated [Pd {C6H2 (CH2CH2NH2)-(OMe) 2, 3, 4}(m-Br)] 2, a complex of homoveratrylamine in the copper-free Sonogashira coupling reaction has been investigated. This complex is a catalyst that is efficient, stable and non-sensitive to air and moisture in the Sonogashira reaction. In this homogeneous catalytic system, various aryl halides were efficiently coupled with phenylacetylene in mostly moderate to good yields in ...