Reaction of enamines with acetals or trialkyl orthoformates activated by Lewis acids

O Takazawa, K Kogami, K Hayashi

Index: Takazawa, Osamu; Kogami, Kunio; Hayashi, Kazuo Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 7 p. 1876 - 1881

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Citation Number: 11

Abstract

Enamines, prepared readily from various carbonyl compounds, react with acetals or trialkyl orthoformates in the presence of Lewis acids such as BF 3· OEt 2 to give corresponding β- alkoxy carbonyl compounds or α-dialkoxymethyl carbonyl compounds in good yields. The reaction of dienamines with acetals or trialkyl orthoformates also selectively gives corresponding β, γ-unsaturated α-(α-alkoxyalkyl) carbonyl compounds or β, γ-unsaturated ...